THE CEES DEKKER DIARIES

The cees dekker Diaries

The cees dekker Diaries

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Nanotechnology delivers An array of opportunities to contribute to biology. Below I'll present examples in which nanofabrication – the opportunity to make confined constructions with Proportions at will – is used to examine the biophysics of single molecules and cells. I will present some examples from our lab:

Our team scientific studies bacterial cell division and is aiming to represent a ‘base up biology’ in synthetic cells that can autonomously divide. Our most important desire lies in mobile division, chromatin construction, and spatial Manage.

[Laughs] ‘It absolutely was surely an incredible possibility! At enough time, I used to be effectively conscious that it could go Incorrect and that I could become significantly less prosperous, but I just overlooked that. Curiosity has constantly been my strongest driving power. And fortuitously it all worked out.’

Our do the job was quickly followed up by Other people, most notably by Phaedon Avouris and colleagues at IBM, who in October 1998 printed their findings on transistors created from solitary- and multi-walled carbon nanotubes in Utilized Physics Letters.

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Cornelis (Cees) Dekker (Haren, 7 april 1959) is een Nederlandse natuurkundige en universiteitshoogleraar verbonden aan de Technische Universiteit Delft. Van 2010 tot en met 2018 was hij tevens directeur van het Kavli Institute of Nanoscience in Delft. Zijn vakgebied is de moleculaire biofysica; hierbij beweegt hij zich op het grensvlak van de natuurkunde en de biologie waarbij hij gebruikmaakt van de zogeheten nanotechnologie, de technieken om aan enkele atomen en moleculen te kunnen meten.

Due to the fact 2000 he moved to solitary-molecule biophysics and nanobiology, with analysis from DNA supercoiling research of nucleosomes and DNA repair proteins to DNA translocation as a result of nanopores. Not long ago his investigation has focused on researching cell division with microorganisms on chip, whilst his top fascination is inside the direction of noticing synthetic cells.

Circulation-pushed rotary motors which include windmills and water wheels drive practical processes in human Culture. Whilst samples of this kind of rotary motors also characteristic prominently in cell biology, their artificial development for the nanoscale has remained challenging. Here we show circulation-driven rotary motion of a self-arranged DNA nanostructure that is certainly docked on to a nanopore in a thin reliable-point out membrane. An elastic DNA bundle self-assembles right into a chiral conformation on phoretic docking on to the stable-point out nanopore, and subsequently shows a sustained unidirectional https://www.ceesdekker.net rotary movement of up to twenty rev s−1.

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It was in the course of this period that Dekker completed exploration on magnetic spin units and on sounds in superconductors and semiconductors.

An integrated microfluidic platform for quantifying drug permeation throughout biomimetic vesicle membranes

Later on we spoke all over again briefly simply because Dekker felt that our discussion of his faith promptly turned purely philosophical, whereas In addition, it concretely will help him in his do the job.

Enable’s first search back again in the intervening time after you made a decision to change your focus from superconductivity and nanotubes to biology at the end of the 1990s.

Supercoiling-dependent DNA binding: quantitative modeling and programs to bulk and one-molecule experiments

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